Limitations of using first-trimester nuchal translucency measurement in routine screening for major congenital heart defects

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Nuchal translucency measurement in first trimester Down syndrome screening.

(1) Approximately three in every four fetuses with Down syndrome have increased nuchal translucency (NT), which is a larger than normal build-up of fluid at the back of the neck. (2) The ultrasound measurement of NT between 11 and 14 weeks' gestation, in combination with the mother's age and the levels of placental biochemical markers in her blood, can be used to detect approximately 84% of fet...

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Evaluation of Nuchal Translucency Measuremen in First Trimester Pregnancy

Background A significant number of pregnancies, particularly in women with previous histories of infertility, are associated with fetal abnormalities. Methods such as the nuchal translucency (NT) measurement enable us to identify more pregnancies with chromosomal abnormalities. MaterialsAndMethods This analytic cross-sectional study was performed in 446 pregnant women at 11-14 weeks gestation, ...

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Evaluation of Nuchal Translucency Measurement in First Trimester Pregnancy

BACKGROUND A significant number of pregnancies, particularly in women with previous histories of infertility, are associated with fetal abnormalities. Methods such as the nuchal translucency (NT) measurement enable us to identify more pregnancies with chromosomal abnormalities. MATERIALS AND METHODS This analytic cross-sectional study was performed in 446 pregnant women at 11-14 weeks gestati...

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Fetal nuchal translucency: ultrasound screening for chromosomal defects in first trimester of pregnancy.

OBJECTIVE To examine the significance of fetal nuchal translucency at 10-14 weeks' gestation in the prediction of abnormal fetal karyotype. DESIGN Prospective screening study. SETTING The Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, London. SUBJECTS 827 fetuses undergoing first trimester karyotyping by amniocentesis or chorionic villus sampling. MAIN OU...

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The role of nuchal translucency in the screening for congenital heart defects.

OBJECTIVE Assess the accuracy of the nuchal translucency (NT) measurement between 11 and 13 weeks and 6 days of gestation as a sonographic marker to screen for congenital heart defects (CHD). METHODS This is a multi-center retrospective study in which singleton gestations of euploid fetuses were analyzed. NT measurement was performed in the first trimester examination when the fetal crown-rum...

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ژورنال

عنوان ژورنال: Ultrasound in Obstetrics and Gynecology

سال: 2001

ISSN: 0960-7692

DOI: 10.1046/j.1469-0705.2001.00342.x